Showing posts with label clinical disorders. Show all posts
Showing posts with label clinical disorders. Show all posts

Friday, February 26, 2016

White matter matters! Brain network communication and synchronization - An oldie-but-goodie (OBG) post

White matter, in contrast to the grey squiggly mass (the cerebrum) that most people associate with the human brain, was for many years the research step-child to the cerebrum. That is no more. White matter, which has been called the brain's subway, super information system, or interstate highway communication system, now has a glass slipper. Research during the past decade has implicated white matter as performing the critical task of connecting and synchronizing different brain regions or networks so they can perform a wide variety of complex human cognitive or motor behaviors. The white matter system is considered the communication backbone system for the flow of information in the brain. Of particular interest (to me) is the parietal-frontal network, which is implicated as central to abstract human intelligence, fluid intelligence (Gf), working memory and attentional control (see prior posts re: the P-FIT model).

In a MindHub white paper I hypothesized that increasing white matter tract integrity may be a key mechanism behind the efficacy of the Interactive Metronome neuro-timing intervention (see figure below). I have gone as far as suggesting that the efficacy of many brain training/fitness programs may stem from a common domain-general effect--improving communication between and within various brain network(s) via more efficient white matter tract speed and communication. [Click on image to enlarge]
White matter integrity or dysfunction as been implicated in a wide variety of cognitive disorders or abilities, including cognitive control, math and intellectual giftedness, fluid intelligence or reasoning, processing speed, reading, decrease in cognitive functioning, meditation, working memory, vascular cognitive impairment, ADHD, autism, and cognitve and language maturation in infants. A sampling of recent white matter research article abstracts I have accumulated can be found by clicking here.
White matter matters!


Sunday, December 20, 2015

Mind wandering, the default network and controlled attention: An OBG video post

(This is an oldie-but-goodie blog post - OBG)

A few interesting video gems for your viewing.

First, forget multitasking and try mono-tasking.  Focus on just one thing...it may be beneficial.


Next, I have frequently blogged about the default mode or default brain network (Brain Clock posts; IM-HOME post).  The default mode (which is estimated to be active approximately 40% of our waking day) has been implicated in how our mind, when idling or resting, is very active--it does not rest while resting.  Difficulty quieting the default network has also been implicated in a variety of clinical disorders such as ADHD, Alzheimers, schizophrenia, and autism. This literature is now frequently referred to as mind wandering research (see Brain Clock mind wandering posts).  The following is a nice brief overview of the default brain network.

I have also suggested that some brain fitness technologies (Interactive Metronome in particular;  conflict of interest disclosure--I serve as a paid external consultant to IM regarding research) are achieving success by either directly or indirectly training controlled, focused attention, which requires shutting down and inhibiting the mind wandering predisposition of the default mode network.  I have posted both a set of PPT slides and the video of my recent IM keynote presentation at the Brain Clock blog where I presented the relevant research and hypotheses in detail.


Finally, a more lengthy, thought provoking video is presented last.  This video makes it clear that the brain is best conceptualized as an evolving interconnected network.


Enjoy.

Friday, November 11, 2011

The brain clock (mental timing) and clinical disorders

The human brain clock is intimately involved in wide array of human cognitive and motor behaviors.  At this blog a number of clincal disorders have been associated with some degree of disturbance or damage to brain mechanisms related to mental timing.  This informaiton is scattered across a variety of posts.  I decided to pull it all together (as of today's date) in this post.

Mental timing (brain clock) has been implicated via research reported at this blog in:

ADHD and attention

Autismhttp://www.brainclock.net/search/label/autism

Various speech and language disorders
Tourette's syndrome

Cerbral palsy

Central auditory processing disorders (CAPD)

Reading disabilities/dyslexia (click here, here and here)

Various dopaminegeric-based disorders
Gate disorders

Stroke related dysfunction

A more detailed reference list of timing-related dysfunctions/disorder (e.g., aging related disorders--Alzheimer's, dementia; ADHD, motor coordination/timing disorders--gait, stroke,swallowing;  speech and language disorders--aphasia/stroke/apraxia/speech; TBI) can be found in special white paper regarding the efficacy of various rhythm-based interventions.